Buy 4-HO-DALT Cas 2173386-70-2

Buy 4-HO-DALT Cas 2173386-70-2

4-HO-DALT, also known as 4-hydroxy-N,N-diallyltryptamine or as daltocin, is a serotonin receptor agonist and serotonergic psychedelic of the tryptamine and 4-hydroxytryptamine families.^[1][2][3] It has been encountered as a novel designer drug.^[4]

4-HO-DALT was not included nor mentioned in Alexander Shulgin‘s book TiHKAL (Tryptamines I Have Known and Loved).^[5] However, in a subsequently released entry, it was briefly mentioned.^[5] He does not appear to have synthesized or tested it and its properties were not described, but Shulgin hypothesized that the drug, in its prodrug form 4-AcO-DALT, would have a very rapid onset of action.^[5] Subsequently, 4-HO-DALT has emerged as a novel designer drug.^[4] It is said to produce hallucinogenic effects similar to those of 4-HO-DiPT and 4-HO-DPT.^[4]

4-HO-DALT binds to many of the serotonin receptors, including the serotonin 5-HT_2A receptor, as well as other targets.^[1][2] The drug acts as a potent full agonist of the serotonin 5-HT_2A and 5-HT_2B receptors, whereas it showed 60-fold lower potency as an agonist of the serotonin 5-HT_2C receptor compared to the serotonin 5-HT_2A receptor.^[2] It produces the head-twitch response, a behavioral proxy of psychedelic-like effects, in rodents.^[1]

Analogues of 4-HO-DALT include diallyltryptamine (DALT), 4-AcO-DALT, 5-MeO-DALT, 4-HO-MALT, psilocin (4-HO-DMT), 4-HO-DET (ethocin), 4-HO-DPT, and 4-HO-DiPT, among others.

4-HO-DALT was first described by Alexander Shulgin in a follow-up entry of TiHKAL (Tryptamines I Have Known and Loved) in 2004.^[5] Subsequently, it was further described in 2017 and thereafter.^[3][1][2] The drug was encountered online as a novel designer drug by 2014.^[4] In 2023, it was found to be sold as an analytical standard.^[4]

4-HO-DALT is not a controlled substance in Canada as of 2025.^[6]