Buy N-HO-AMT Cas 63-33-2

Buy N-HO-AMT Cas 63-33-2

N-Hydroxy-AMT, or N-HO-AMT, also known as N-hydroxy-α-methyltryptamine, is a possible psychedelic drug of the tryptamine and α-alkyltryptamine families related to α-methyltryptamine (AMT).^[1] It is the N–hydroxy derivative of AMT.^[1] The drug was not mentioned in Alexander Shulgin‘s 1997 book TiHKAL (Tryptamines I Have Known and Loved) and its properties and effects in humans are unknown.^[2] In preclinical research, N-hydroxy-AMT produces stimulant-like effects in mice such as hyperlocomotion and antagonism of hexobarbital-induced sleeping time, pressor effects in cats, and a psychedelic-like rage reaction in cats.^[1][3][4] Unlike AMT, it is not a monoamine oxidase inhibitor (MAOI) in vitro.^[1] N-Hydroxy derivatives of phenethylamines such as the HOT-x series like HOT-2 as well as MDOH may act as prodrugs of their N-unsubstituted forms.^[5] The chemical synthesis^[1] and analytical detection of N-hydroxy-AMT have been described.^[6] N-Hydroxy-AMT was first described in the scientific literature by F. Benington and colleagues in 1965.^[1][6] It is not a controlled substance in Canada as of 2025.^[7]