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CUMYL-4CN-BINACA (also known as CUMYL-CYBINACA or SGT-78) is an indazole-3-carboxamide based synthetic cannabinoid that has been sold online as a designer drug.[3][4][5][6][7][8] It is a potent agonist for cannabinoid receptors CB1 and CB2, with in vitro EC50 values of 0.58 nM and 6.12 nM, respectively.[9] In mice, CUMYL-4CN-BINACA produces hypothermic and pro-convulsant effects via the CB1 receptor,[9] and anecdotal reports suggest it has an active dose of around 0.1 mg in humans.[10]

CUMYL-4CN-BINACA is metabolized to produce cyanide, raising concerns about liver toxicity.[8] There is one reported case of hyperthermia, rhabdomyolysis, and kidney failure associated with its use.[11]

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SGT-78 for Sale – Buy Premium Research Chemical from MedAxis

Looking for a trusted source for SGT-78 for sale? MedAxis supplies premium, lab-verified SGT-78 (Cumyl-4CN-BINACA) for forensic, pharmacological, and analytical research. Our rigorous quality control and compliance protocols make us the definitive source for reliable research materials.

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Why Choose MedAxis for SGT-78?

MedAxis eliminates the uncertainty of sourcing advanced research chemicals. We provide certified purity, secure global logistics, and expert support to ensure your research maintains the highest standards of integrity and reliability.

We provide:

  • We Deliver Analytical-Grade SGT-78: Our SGT-78 for sale meets strict research specifications. We verify every batch through independent third-party analysis, providing certificates of analysis (CoA) confirming high purity (>98%) and accurate compound identity Cayman Chemical.

  • We Ensure Secure, Compliant Shipping: We manage discreet, tamper-evident shipping to verified research institutions worldwide, including the USA, UK, Canada, Europe, and Australia. Our logistics fully comply with international regulations for the transport of research materials.

  • We Offer Specialized Research Support: Our team provides detailed technical information and handling protocols tailored for advanced cannabinoid receptor studies and forensic toxicology.


Understanding SGT-78 (Cumyl-4CN-BINACA)

SGT-78 (1-(4-cyanobutyl)-N-(1-methyl-1-phenylethyl)-1H-indazole-3-carboxamide) is a synthetic cannabinoid receptor agonist of the indazole-3-carboxamide class. Its structural features, including the cumyl and 4-cyanobutyl groups, are significant for its receptor binding profile and make it a subject of interest in controlled pharmacological research PubChem.


Research Applications of SGT-78

SGT-78 serves as a critical reagent in lawful, controlled scientific investigations, including:

  • Neuropharmacological Research: Studying the affinity and functional activity of novel synthetic cannabinoids at CB1 and CB2 receptors.

  • Metabolic & Forensic Analysis: Investigating phase I and II metabolic pathways to identify biomarkers for detection in biological samples Drug Testing and Analysis.

  • Toxicological Profiling: Supporting research into the physiological and behavioral effects of novel psychoactive substances (NPS) in validated experimental models.

Critical Safety & Legal Notice:
SGT-78 is a potent synthetic cannabinoid intended exclusively for in vitro research in controlled laboratory environments by qualified professionals. It is not for human or animal consumption. Researchers are solely responsible for ensuring all activities comply with their local, national, and international laws regarding controlled substances and research chemicals NIDA.


Frequently Asked Questions (FAQs)

Q: Is it legal to purchase SGT-78 from MedAxis?
A: We supply SGT-78 strictly to verified and accredited research organizations for lawful scientific investigation. Compliance with all applicable laws is the responsibility of the purchasing institution.

Q: What documentation is provided?
A: Each shipment includes a comprehensive Certificate of Analysis (CoA) from an independent laboratory, detailing purity (>98%), analytical data (HPLC, MS), and batch information.

Q: How is the product shipped and packaged?
A: We use professional, discreet packaging designed to ensure product integrity and confidentiality during transit. All shipments are fully traceable.

Q: Do you ship to my country?
A: We ship to numerous countries globally. Please contact us with your institutional details to confirm shipping eligibility and any specific import requirements.

Q: What are the storage conditions?
A: For optimal long-term stability, store in a cool, dry place, protected from light. We recommend storage at -20°C or below.

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Cumyl-4CN-Binaca, also known as Cumyl-Cybinaca or SGT-78, is a powerful synthetic cannabinoid that has gained popularity among cannabinoid enthusiasts worldwide. As the most reliable supplier of SGT-78 powder and other synthetic cannabinoids, Jason Research Chemicals is dedicated to providing customers in Canada, Australia, USA, New Zealand, Europe, and beyond with the highest quality products.

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At Jason Research Chemicals, we understand the importance of quality and safety when it comes to synthetic cannabinoids. That’s why we source our Cumyl-4CN-Binaca from reputable manufacturers and conduct rigorous testing to ensure the purity and potency of our products. We prioritize the well-being of our customers and strive to provide them with a reliable and consistent supply of synthetic cannabinoids.

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Cumyl-4CN-Binaca, also known as CUMYL-CYBINACA or SGT-78, belongs to the indazole-3-carboxamide family of synthetic cannabinoids. Its chemical structure includes a cumyl group attached to the amino group of the indazole ring, giving it its distinct properties. This compound has been the subject of extensive research due to its potential therapeutic applications and its ability to interact with the endocannabinoid system.

One of the key characteristics of Cumyl-4CN-Binaca is its high affinity for the CB1 and CB2 receptors in the brain and peripheral tissues. These receptors are part of the endocannabinoid system, which plays a crucial role in regulating various physiological processes such as pain perception, appetite, mood, and immune function. By binding to these receptors, Cumyl-4CN-Binaca can modulate the activity of the endocannabinoid system, leading to a wide range of effects.

Research has shown that Cumyl-4CN-Binaca exhibits potent agonist activity at the CB1 and CB2 receptors, meaning it activates these receptors and mimics the effects of naturally occurring cannabinoids. This activation can result in a variety of effects, including relaxation, euphoria, pain relief, and appetite stimulation. However, it is important to note that the precise effects of Cumyl-4CN-Binaca can vary depending on factors such as dosage, route of administration, and individual sensitivity.

In addition to its interaction with the endocannabinoid system, Cumyl-4CN-Binaca also has the potential to interact with other neurotransmitter systems in the brain. For example, it has been found to inhibit the reuptake of the neurotransmitter serotonin, which is involved in mood regulation. This dual mechanism of action makes Cumyl-4CN-Binaca a compound of great interest for researchers studying the neuropharmacology of synthetic cannabinoids.

Due to its potent effects and high affinity for cannabinoid receptors, Cumyl-4CN-Binaca has gained popularity among enthusiasts seeking novel psychoactive substances. However, it is important to emphasize that the use of synthetic cannabinoids carries significant risks. These compounds have been associated with a range of adverse effects, including anxiety, paranoia, hallucinations, and cardiovascular complications. Furthermore, the long-term effects of Cumyl-4CN-Binaca on human health are still largely unknown, highlighting the need for further research.

Overall, Cumyl-4CN-Binaca is a fascinating compound with unique properties that make it a subject of interest for researchers and enthusiasts alike. Its potent effects on the endocannabinoid system and potential interactions with other neurotransmitter systems make it a compound worth studying in the context of both therapeutic applications and recreational use. However, it is crucial to approach the use of synthetic cannabinoids with caution and prioritize safety and responsible experimentation.

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There are several reasons why Cumyl-4CN-Binaca is the top choice for researchers and enthusiasts:

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  2. Reliability: At Jason Research Chemicals, we prioritize quality and reliability. We ensure that our Cumyl-4CN-Binaca powder is of the highest purity, allowing researchers to conduct accurate and reliable experiments. Our rigorous quality control measures, including third-party testing, guarantee the consistency and purity of our product, providing researchers with confidence in their findings.
  3. Wide Availability: Whether you’re in Canada, Australia, USA, New Zealand, or Europe, we offer worldwide shipping so that researchers from around the globe can access our Cumyl-4CN-Binaca powder with ease. Our efficient and reliable shipping services ensure timely delivery, allowing researchers to commence their experiments without delay.
  4. Trusted Supplier: With years of experience in the industry, Jason Research Chemicals has established itself as a trusted supplier of synthetic cannabinoids. Our commitment to quality and customer satisfaction sets us apart from the competition. We prioritize building long-term relationships with our customers, providing them with exceptional service, and ensuring their research needs are met. Our knowledgeable and dedicated team is always available to address any inquiries or concerns.

Choosing Cumyl-4CN-Binaca from Jason Research Chemicals ensures that researchers have access to a potent and reliable synthetic cannabinoid. Our commitment to quality, worldwide availability, and exceptional customer service make us the preferred choice for researchers and enthusiasts alike. Join the growing community of researchers who trust Cumyl-4CN-Binaca for their groundbreaking studies and discoveries in the field of synthetic cannabinoids.

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Purchasing Cumyl-4CN-Binaca from Jason Research Chemicals is a simple and straightforward process. Follow these steps to get your hands on this exceptional synthetic cannabinoid:

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  2. Select Your Quantity: Choose the desired quantity of Cumyl-4CN-Binaca powder that suits your research needs. We offer a range of options to accommodate different research requirements. Whether you need a small sample for initial testing or a larger quantity for extensive studies, we have you covered. JWH-018
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SGT-78 (also known as CUMYL-CYBINACA or CUMYL-4CN-BINACA) is an indazole-3-carboxamide based synthetic cannabinoid that has been sold online as a designer drug. While the in vitro activity of this compound is not disclosed in the associated patent, anecdotal reports suggest it is a potent cannabinoid agonist with an active dose of around 0.1mg.

SGT-78 and all other synthetic cannabinoids sold on this website are intended for research and forensic applications. The research chemical called SGT-78 is a designer drug with pronounced physiological and psychoactive effects and has the molecular formula C22H24N4O. The formula weight has the value 360.5 g/mol.

The toxicological and physiological properties of SGT-78 are not known.
 Synthetic cannabinoids like SGT-78 might display high affinity for peripheral CB1 and CB2 cannabinoid receptors.

1-(4-cyanobutyl)-N-(1-methyl-1-phenylethyl)-1H-indazole-3-carboxamide and all other designer drugs sold on this website are intended for research and forensic applications.

One study conducted on SGT-78 characterized the metabolism as well as the clearance of the research chemical using rat and human liver microsomes along with hepatocytes, which were used to compare to urine sampling and in vivo rat plasma. The study also examined hypothermia. The incubation with the microsomes showed fast metabolic clearance however, in the metabolism in vivo took longer which allowed detection in the rat plasma. The research chemical did show hypothermic effects with 28 metabolites able to be identified.

Other research shows that SGT-78 is an agonist at the receptors known as a cannabinoid. Being an analogue of a similar compound the difference noted was that an N-cumyl group replaced the N-adamantyl group. For laboratories that wish to conduct studies on SGT-78, it is important to purchase from a research chemical manufacturer that includes all data regarding how to safely handle the chemical as well as how to protect the shelf life of the chemical.

More research needs to be conducted in laboratories until data can be compiled to learn compound properties. Currently, a compound only intended for scientific and forensic research and is NOT for human consumption.

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Buy CUMYL-4CN-BINACA (SGT-78) Powder Online | Synthetic Cannabinoid | Global Chem Market

CUMYL-4CN-BINACA, widely recognized in the research community as SGT-78, is a potent synthetic cannabinoid belonging to the indazole-3-carboxamide family. As a highly efficacious agonist of the CB_1 and CB_2$ receptors, it has become a primary subject for forensic analysis and biochemical studies. At Global Chem Market, we provide SGT-78 in its purest powder form, ensuring consistent results for laboratory and analytical applications worldwide.

Chemical Formula and Chemistry – Buy CUMYL-4CN-BINACA Online USA

The chemical structure of CUMYL-4CN-BINACA is defined as 1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide. It is characterized by a terminal aliphatic nitrile group on a 4-cyanobutyl chain, which distinguishes it from other cumyl-derived cannabinoids. Its chemical formula is:

C_{22}H_{24}N_{4}O

With a molar mass of approximately 360.46 g/mol, the presence of the nitrile group plays a significant role in its metabolic pathways and binding affinity, making it a unique specimen for chemical profiling.

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We are the prime vendor and supplier in the online market and are dealing with SGT-78 at affordable rates. You can also share your requirements with us and get them all completed inside a short timeframe. We will reach your mentioned location with the complete order. Buy SGT-78 today!

We have a highly dedicate network that all the products are delivered to you on time and dispatched on time. We are trustworthy team members, where customer satisfaction is our ultimate goal. You can make your wise decision by placing your order with us. We assure you that we won’t let down your expectations in terms of quality and quantity.SGT-78 CUMYL-4N-BINACA Powder for sale

In addition to this, we continually look forward to expanding our business in all parts of the country and hence every time we usually add more and more products in our catalogue. We stock and help you find the best quality of products at the right time.

Available Form – CUMYL-4CN-BINACA Supplier USA

Our CUMYL-4CN-BINACA (SGT-78) is available as a high-purity crystalline powder. This form is preferred by researchers due to its stability and ease of measurement for various experimental formulations. The powder is typically white to off-white and is stable at room temperature, though we recommend long-term storage at -20°C to maintain its chemical integrity for up to 2 years.

Primary Uses- Order SGT-78 Powder Online

SGT-78 is intended strictly for forensic, laboratory, and scientific research purposes. It is frequently used as an analytical reference standard to help toxicology labs identify new psychoactive substances (NPS). In a research setting, it is used to study the binding kinetics of the cannabinoid system and the physiological impact of synthetic agonists on receptor signaling. It is not approved for human or veterinary consumption.

Side Effects and Safety Profile

Because CUMYL-4CN-BINACA is a highly potent CB_1 receptor agonist, it is associated with significant physiological risks if handled improperly. Research indicates that exposure can lead to severe adverse effects, including pro-convulsant activity (seizures), hyperthermia, and tachycardia. Detailed studies on animal models have also linked the substance to oxidative stress and potential renal toxicity. Standard laboratory safety protocols, including the use of gloves and respiratory protection, must be followed at all times

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