Buy 3-Thiomescaline (3-TM) Cas 78335-85-0

Buy 3-Thiomescaline (3-TM) Cas 78335-85-0

3-Thiomescaline (3-TM), also known as 3-methylthio-4,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and scaline families related to mescaline (3,4,5-trimethoxyphenethylamine).^[1][2][3][4] It is the analogue of mescaline in which the methoxy group at the 3 position has been replaced with a methylthio group.^[1][2][3][4] The drug is one of two possible thiomescaline (TM) positional isomers, the other being 4-thiomescaline (4-TM).^[1][2][3][4]

In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists 3-TM’s dose as 60 to 100 mg orally and its duration as 8 to 12 hours.^[1][2][3][4] Its onset is within 1 hour.^[1] The drug has about 4 to 6 times the potency of mescaline.^[1][2][3][4] The effects of 3-TM have been reported to include color enhancement, closed-eye imagery and fantasy, no open-eye visuals, auditory–visual synaesthesia with music, intoxication, relaxation, feelings of sublimity and peacefulness, conflicting energy, tension, paranoia, irritability, and guardedness.^[1][4]

The chemical synthesis of 3-TM has been described.^[1][4]

3-TM was first described in the literature by Shulgin and colleagues by 1981.^[4] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.^[1]