Buy 5-MeO-T-NB3OMe Cas 1648553-42-7
Buy 5-MeO-T-NB3OMe Cas 1648553-42-7
5-MeO-T-NB3OMe, or 5MT-NB3OMe, also known as N-(3-methoxybenzyl)-5-methoxytryptamine, is a serotonin receptor modulator and psychedelic drug of the tryptamine, 5-methoxytryptamine, and N-benzyltryptamine families related to the 25-NB (NBOMe) psychedelics.[1][2][3][4] It is a positional isomer of 5-MeO-T-NBOMe (5-MeO-T-NB2OMe).[2]
The drug shows affinity for many serotonin receptors and acts as an agonist of the serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptors.[4] It had similar affinity and activational potency at the human serotonin 5-HT2A receptor as 5-MeO-T-NBOMe.[4] In addition, the drug had around 10-fold lower affinity for the human serotonin 5-HT2A receptor as 25I-NBOMe (25I-NB2OMe) but showed similar activational potency at this receptor as 25I-NBOMe.[4] 5-MeO-T-NB3OMe produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents.[2][4] It had similar potency in this test as 5-MeO-T-NBOMe and 25I-NB3OMe, but showed dramatically or 42- to 45-fold lower potency than 25I-NBOMe.[2][4]
The chemical synthesis of 5-MeO-T-NB3OMe has been described.[4] Various analogues of 5-MeO-T-NB3OMe besides 5-MeO-T-NBOMe have also been described.[2][4][5][6]
5-MeO-T-NB3OMe was first described in the scientific literature by David E. Nichols and colleagues in 2015.[1][2][3][4] It is not a controlled substance in Canada as of 2025.[7] It is also not an explicitly controlled substance in the United States,[8] but it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.
Reviews
There are no reviews yet.